Funded Research - Lupus Research

2021 Funded Grants

Identification of new genes that restrict TLR7 responses to self nucleic acids

Gregory Barton, PhD
University of California, Berkeley

Targeting the proteoglycan switch for lupus therapy

Nunzio Bottini, MD, PhD
University of California, San Diego

Role of novel metabolite-receptor pathway in protection from lupus

Jason Cyster, PhD
University of California, San Francisco

Insights into lupus heterogeneity by single-cell profiling of B cell activation

Maria Gutierrez-Arcelus, PhD
Boston Children's Hospital

Linking the microbiome and the B cell repertoire to lupus nephritis

Bart Lambrecht, MD, PhD
VIB-UGent Center for Inflammation Research

Targeting pathogenic endothelial dysfunction in lupus nephritis

James Oates, MD
Medical University of South Carolina

Targeted regulatory T cells (Tregs) to treat lupus nephritis

Joshua Ooi, PhD
Monash University

Mechanisms of SCARF1 in regulating SLE

Zaida Ramirez-Ortiz, PhD
University of Massachusetts Medical School

Beyond serology: Improving the prediction and treatment of lupus with single cell Omics

Joanne Reed, PhD
Westmead Institute

The role of polyamine catabolism in the development of lupus

Betty Tsao, PhD
Medical University of South Carolina

Diversity of anti-NMDA receptor autoantibodies in lupus patients

Lonnie Wollmuth, PhD
Stony Brook University

2020 Funded Grants

Erythroid mitochondrial dysfunction in lupus pathogenesis

Simone Caielli, PhD
Weill Cornell Medical College

Mechanisms of vascular injury and dysfunction in pediatric lupus

Joyce Chang, MD
Boston Children's Hospital

cGAMP as an immune transmitter of the interferon response

Keith B. Elkon, MD
University of Washington

Multiplexed single-cell imaging in pediatric lupus nephritis

Elena Wen-Yuan Hsieh, MD
University of Colorado

Targeting a novel population of innate-like CD8+ Treg in lupus

Vipin Kumar, PhD
The Regents of University of California, San Diego

Modeling cognitive impairment in patients with systemic lupus erythematosus

Zahi Touma, MD, PhD
University Health Network

Targeting mTORC2 for lupus treatment

Hu Zeng, PhD
Mayo Clinic, Rochester, MN

2019 Funded Grants

The role of microglial subsets in driving neuropsychiatric symptoms of SLE

Carla Cuda, PhD
Northwestern University Feinberg School of Medicine

Contribution of dysregulated granulopoiesis to SLE pathogenesis

Neelakshi Jog, PhD
Oklahoma Medical Research Foundation

Shining a light on the drivers of photosensitivity in systemic lupus

Michelle Kahlenberg, MD, PhD
University of Michigan

Establishing the role of apoptosis and mtDNA in the pathobiology of lupus

Benjamin Kile, PhD
Monash University, Clayton, Australia

New mechanisms for thrombosis and atherosclerosis in SLE and APS

Yee Ling Wu, PhD
Loyola University Chicago Health Sciences Division

2018 Funded Grants

Ferroptosis as a novel driver of inflammation in lupus nephritis

Erika Boesen, PhD
University of Nebraska Medical Center

Examining the role of T cell exhaustion in lupus pathogenesis

Jeremy Tilstra, MD, PhD
University of Pittsburgh

2017 Funded Grants

Immunotargeting of T follicular helper (Tfh) cells for SLE treatment

Andre Ballesteros-Tato, PhD
University of Alabama at Birmingham

Unexpected role(s) for IRF5 risk variants in SLE pathogenesis

Betsy Jo Barnes, PhD
The Feinstein Institute for Medical Research

Neutrophil elastase as a therapeutic target in lupus

Jason S. Knight, MD, PhD
University of Michigan Medical School

Targeting nicotinic receptors to reduce inflammation associated with SLE

Keisa Williams Mathis, PhD
University of Texas Health Science Center at Fort Worth

Regulation of CD11c+Tbet+ B cells in lupus

Alessandra B. Pernis, MD
The Hospital for Special Surgery

Targeting EZH2 in lupus

Amr Sawalha, MD
University of Pittsburgh

2016 Funded Grants

Multi-level biomarkers for psychiatric disorders in pediatric lupus

Andrea Knight, MD, FRCPC
The Hospital for Sick Children