Lupus Innovation Award (LIA)
2021 Funded Grants
Identification of new genes that restrict TLR7 responses to self nucleic acids
Gregory Barton, PhDUniversity of California, Berkeley
Targeting the proteoglycan switch for lupus therapy
Nunzio Bottini, MD, PhDUniversity of California, San Diego
Role of novel metabolite-receptor pathway in protection from lupus
Jason Cyster, PhDUniversity of California, San Francisco
Insights into lupus heterogeneity by single-cell profiling of B cell activation
Maria Gutierrez-Arcelus, PhDBoston Children's Hospital
Linking the microbiome and the B cell repertoire to lupus nephritis
Bart Lambrecht, MD, PhDVIB-UGent Center for Inflammation Research
Targeting pathogenic endothelial dysfunction in lupus nephritis
James Oates, MDMedical University of South Carolina
Targeted regulatory T cells (Tregs) to treat lupus nephritis
Joshua Ooi, PhDMonash University
Mechanisms of SCARF1 in regulating SLE
Zaida Ramirez-Ortiz, PhDUniversity of Massachusetts Medical School
Beyond serology: Improving the prediction and treatment of lupus with single cell Omics
Joanne Reed, PhDWestmead Institute
The role of polyamine catabolism in the development of lupus
Betty Tsao, PhDMedical University of South Carolina
Diversity of anti-NMDA receptor autoantibodies in lupus patients
Lonnie Wollmuth, PhDStony Brook University
2020 Funded Grants
Erythroid mitochondrial dysfunction in lupus pathogenesis
Simone Caielli, PhDWeill Cornell Medical College
Mechanisms of vascular injury and dysfunction in pediatric lupus
Joyce Chang, MDBoston Children's Hospital
cGAMP as an immune transmitter of the interferon response
Keith B. Elkon, MDUniversity of Washington
Multiplexed single-cell imaging in pediatric lupus nephritis
Elena Wen-Yuan Hsieh, MDUniversity of Colorado
Targeting a novel population of innate-like CD8+ Treg in lupus
Vipin Kumar, PhDThe Regents of University of California, San Diego
Modeling cognitive impairment in patients with systemic lupus erythematosus
Zahi Touma, MD, PhDUniversity Health Network
Targeting mTORC2 for lupus treatment
Hu Zeng, PhDMayo Clinic, Rochester, MN
2019 Funded Grants
The role of microglial subsets in driving neuropsychiatric symptoms of SLE
Carla Cuda, PhDNorthwestern University Feinberg School of Medicine
Contribution of dysregulated granulopoiesis to SLE pathogenesis
Neelakshi Jog, PhDOklahoma Medical Research Foundation
Shining a light on the drivers of photosensitivity in systemic lupus
Michelle Kahlenberg, MD, PhDUniversity of Michigan
Establishing the role of apoptosis and mtDNA in the pathobiology of lupus
Benjamin Kile, PhDMonash University, Clayton, Australia
New mechanisms for thrombosis and atherosclerosis in SLE and APS
Yee Ling Wu, PhDLoyola University Chicago Health Sciences Division
2018 Funded Grants
Ferroptosis as a novel driver of inflammation in lupus nephritis
Erika Boesen, PhDUniversity of Nebraska Medical Center
Examining the role of T cell exhaustion in lupus pathogenesis
Jeremy Tilstra, MD, PhDUniversity of Pittsburgh
2017 Funded Grants
Immunotargeting of T follicular helper (Tfh) cells for SLE treatment
Andre Ballesteros-Tato, PhDUniversity of Alabama at Birmingham
Unexpected role(s) for IRF5 risk variants in SLE pathogenesis
Betsy Jo Barnes, PhDThe Feinstein Institute for Medical Research
Neutrophil elastase as a therapeutic target in lupus
Jason S. Knight, MD, PhDUniversity of Michigan Medical School
Targeting nicotinic receptors to reduce inflammation associated with SLE
Keisa Williams Mathis, PhDUniversity of Texas Health Science Center at Fort Worth
Regulation of CD11c+Tbet+ B cells in lupus
Alessandra B. Pernis, MDThe Hospital for Special Surgery
Targeting EZH2 in lupus
Amr Sawalha, MDUniversity of Pittsburgh
2016 Funded Grants
Multi-level biomarkers for psychiatric disorders in pediatric lupus
Andrea Knight, MD, FRCPCThe Hospital for Sick Children