Funded Research - Lupus Research

2020 Funded Grants

Erythroid mitochondrial dysfunction in lupus pathogenesis

Simone Caielli, PhD
Weill Cornell Medical College

Mechanisms of vascular injury and dysfunction in pediatric lupus

Joyce Chang, MD
The Children's Hospital of Philadelphia

cGAMP as an immune transmitter of the interferon response

Keith B. Elkon, MD
University of Washington

Multiplexed single-cell imaging in pediatric lupus nephritis

Elena Wen-Yuan Hsieh, MD
University of Colorado

Targeting a novel population of innate-like CD8+ Treg in lupus

Vipin Kumar, PhD
The Regents of University of California, San Diego

Modeling cognitive impairment in patients with systemic lupus erythematosus

Zahi Touma, MD, PhD
University Health Network

Targeting mTORC2 for lupus treatment

Hu Zeng, PhD
Mayo Clinic, Rochester, MN

2019 Funded Grants

The role of microglial subsets in driving neuropsychiatric symptoms of SLE

Carla Cuda, PhD
Northwestern University Feinberg School of Medicine

Contribution of dysregulated granulopoiesis to SLE pathogenesis

Neelakshi Jog, PhD
Oklahoma Medical Research Foundation

Shining a light on the drivers of photosensitivity in systemic lupus

Michelle Kahlenberg, MD, PhD
University of Michigan

Establishing the role of apoptosis and mtDNA in the pathobiology of lupus

Benjamin Kile, PhD
Monash University, Clayton, Australia

New mechanisms for thrombosis and atherosclerosis in SLE and APS

Yee Ling Wu, PhD
Loyola University Chicago Health Sciences Division

2018 Funded Grants

Ferroptosis as a novel driver of inflammation in lupus nephritis

Erika Boesen, PhD
University of Nebraska Medical Center

Lymphatic regulation and photosensitivity

Theresa Lu, MD, PhD
The Hospital for Special Surgery

Genetically engineering regulatory T cells to treat SLE

Joshua Ooi, PhD
School of Clinical Sciences, Monash University

Examining the role of T cell exhaustion in lupus pathogenesis

Jeremy Tilstra, MD, PhD
University of Pittsburgh

Epigenetic regulation of Il2 by ATF7ip – implications for SLE

Michael Waterfield, MD, PhD
University of California, San Francisco

2017 Funded Grants

Immunotargeting of T follicular helper (Tfh) cells for SLE treatment

Andre Ballesteros-Tato, PhD
University of Alabama at Birmingham

Unexpected role(s) for IRF5 risk variants in SLE pathogenesis

Betsy Jo Barnes, PhD
The Feinstein Institute for Medical Research

Neutrophil elastase as a therapeutic target in lupus

Jason S. Knight, MD, PhD
University of Michigan Medical School

Characterization of chemokine producing effector B cells in SLE

Frances E. Lund, PhD
University of Alabama at Birmingham

Targeting nicotinic receptors to reduce inflammation associated with SLE

Keisa Williams Mathis, PhD
University of Texas Health Science Center at Fort Worth

Regulation of CD11c+Tbet+ B cells in lupus

Alessandra B. Pernis, MD
The Hospital for Special Surgery

Mechanisms of the autoimmune germinal center response in SLE

Ziaur Rahman, MD, PhD
Pennsylvania State University College of Medicine

Targeting EZH2 in lupus

Amr Sawalha, MD
University of Pittsburgh

2016 Funded Grants

Autophagy components and B cell activation during SLE

Mridu Acharya, PhD
Benaroya Research Institute at Virginia Mason

Anti-BDCA 2-targeted therapy for SLE

Natalia Giltiay, PhD
University of Washington

B cell-intrinsic cytokine reg of spontaneous germinal ctr formation in SLE

Shaun Jackson MD, PhD
Seattle Children’s Hospital

Multi-level biomarkers for psychiatric disorders in pediatric lupus

Andrea Knight, MD, FRCPC
The Hospital for Sick Children

Mitochondria, caspases and type I interferons in autoimmunity

Anthony Rongvaux, PhD
Fred Hutchinson Cancer Research Center

Oxidized mitochondrial DNA employs APEX1 in neutrophils to control lupus

Zhiqiang Zhang, PhD
The Methodist Hospital Research Institute

A novel approach for treating lupus by inhibiting Fli1 transcription factor

John Zhang, PhD
Medical University of South Carolina