Lupus Mechanisms and Targets Award (LMTA)
2023 Funded Grants
Blockade of Human CD21 with a Humanized Blocking Antibody
Michael Carroll, Ph.D.
Boston Children's Hospital
Uncovering the Molecular Signatures of Treatment Response in LN
Shaun Jackson, M.D., Ph.D.
Seattle Children's Hospital
Targeting NETs in Obstetric APS
Jason Knight, M.D., Ph.D.
The Regents of the University of Michigan
S100A4 in Lupus Nephritis
Chandra Mohan, M.D., Ph.D.
University of Houston
Dissecting the Transition from Autoreactivity to Disease in Lupus Nephritis
Boris Reizis, Ph.D.
New York University Grossman School of Medicine
Precision Targeting of Lupus IGHV4-34+ Pathogenic B Cells with CAR T Cells
Marco Ruella, M.D.
The Trustees of the University of Pennsylvania
PARP7 as a New Negative Feedback Regulator of Type I Interferon Signaling
Nan Yan, Ph.D.
The University of Texas Southwestern Medical Center
2022 Funded Grants
SGLT2 inhibition as a novel treatment for lupus nephritis
Jennifer Anolik, MD, PhD
University of Rochester
New molecular pathways leading to IRF5-mediated SLE
Betsy Barnes, PhD
The Feinstein Institutes for Medical Research
Targeting Hippo signaling to downregulate IFN production in SLE
J. Michelle Kahlenberg, MD, PhD
University of Michigan
Targeting CXCR6+ T cell recruitment and memory in cutaneous lupus
Jillian Richmond, PhD
University of Massachusetts Chan Medical School
2020 Funded Grants
In situ adaptive immunity in lupus tubulointerstitial inflammation
Marcus Clark, MD
The University of Chicago
IgA-containing immune complexes in SLE
Jessica A. Hamerman, PhD
Benaroya Research Institute at Virginia Mason
Dynamic regulation of signaling pathways in SLE
Alessandra Pernis, MD
The Hospital for Special Surgery
Candidate pathobiont in lupus: genomic variation and pathogenesis
Gregg J Silverman, MD
New York University School of Medicine
Redesigning Dnase1L3 for the treatment of systemic lupus erythematosus
Roger Bryan Sutton, PhD
Texas Tech University Health Sciences Center
2019 Funded Grants
Targeting the inactive X for correcting dosage imbalances in lupus
Montserrat Anguera, PhD
University of Pennsylvania
Intrinsic B cell epigenetic mediators as therapeutic targets in lupus
Paolo Casali, MD
University of Texas Health Science Center at San Antonio
Relieving ER stress in lupus neutrophils
Jason Knight, MD, PhD
University of Michigan, Ann Arbor