Leading the way to a cure

Our Funded Research


Lupus is a very complex autoimmune disease that is difficult to diagnose, treat, and defeat. This is why the Alliance for Lupus Research (ALR) is working hard to fund promising scientific investigations conducted by the best and brightest minds in lupus research.

We believe it is possible to beat lupus for good—and that the answer is research.

The ALR's approach is simple: Fight the disease on many fronts.

Our aim is to facilitate the advancement of the conceptual understanding of lupus, the development of an array of more effective treatments with fewer side effects, and ultimately the cure for lupus.

In little more than a decade, the ALR has grown to become the world's largest private funder of lupus research.

No other non-governmental organization has done more to combat this awful disease.

The ALR has committed over $172 million to lupus research — giving hope to those with the disease that viable treatment options and a cure are on the horizon.

Over 1.5 million Americans have lupus — that’s more than those affected with cerebral palsy, multiple sclerosis, cystic fibrosis & leukemia.

Click here to learn more about our current research portfolio

An Overview of Alliance for Lupus Research accomplishments

Since our inception in 1999, the ALR has funded 159 pioneering investigations and has made astonishing discoveries that have revolutionized the way lupus research is conducted. Such remarkable progress was undreamed of back then:

With ALR funding, scientists in the SLEGEN Consortium—for the first time—uncovered several of the genes responsible for lupus. Now scientists everywhere have a roadmap for targeting these specific genes.

  • In a current ALR collaboration that builds on the SLEGEN discovery, researchers are using a new technology called the ImmunoChip to study hundreds of thousands of genes and their variants in a large number of participants.
  • The ALR was among the first to fund an early exploration of B Cells—opening an avenue of investigation that is now widely believed to have enormous potential. In fact, the first new lupus drug to be approved by the FDA is an outcome of that study.
  • For the first time in decades, promising drugs are in the pipeline. A number of the studies that have lead to these new treatments received ALR funding.
  • We've sparked strong interest among leading researchers, so that more of them work and collaborate on this disease today than ever before

Click here to learn more about our Research funding mechanisms

1.5 million

people in the U.S. have Lupus.

172 million

dollars committed to lupus research by the Lupus Research Alliance.

We're walking across the United States to raise awareness and funds for lupus research.


Show your support by visiting the Lupus Research Alliance online store. Discover the perfect gift, or prepare for a walk with our selection of apparel and accessories.

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