3 Questions with Dr. Ashira Blazer
March 8, 2023 As part of our researcher interview series, we are featuring 3 Questions with Ashira Blazer, MD, at Hospital for Special Surgery — one of our Diversity in Lupus Research Award recipients. Below Dr. Blazer explains why she focused her career on lupus, and explains how the project LRA is funding will help […]
LRA Researchers Reveal New Drug Targets at Leading Immunology Conference
May 22, 2019 Data presented by several Lupus Research Alliance-funded scientists at the recent American Association of Immunologists Annual Meeting suggests many avenues for new lupus treatments. Some scientists presented data posing new targets for drug development, while others have discovered cells that suppress the immune response and could be harnessed as treatments. Reining in […]
New LRA-Supported Study Discovers STAT1, a Highly Specific Target for Potential New Therapy
April 23, 2020 A new study supported by the Lupus Research Alliance discovered a way that harmful immune responses in lupus and lupus nephritis could be stopped while protective immune responses, such as those to infection, are preserved. The findings were published in the prestigious Journal of Immunology and add evidence to the value of […]
LRA-Funded Scientists Command Attention at 2019 ACR/ARP
November 14, 2019 The Lupus Research Alliance was proud of the unprecedented number of the studies supported by the Alliance chosen for presentation at the 2019 ACR/ARP Annual Meeting, the world’s largest rheumatology conference. A total of 19 studies were shared in oral presentations to large audiences, while 13 were presented as posters, which allow […]
Promising Results from AMP
October 30, 2018 The Lupus Research Alliance is one of the sponsors of the Accelerating Medicines Partnership in Rheumatoid Arthritis and Lupus (AMP RA/Lupus), a public-private partnership between the National Institutes of Health, the U.S. Food and Drug Administration and several pharmaceutical companies and nonprofit organizations. AMP aims to speed the development of new therapies, […]
New LRA-Supported Study Provides Clue to Potential New Treatment Target
February 27, 2020 A new study supported by the Lupus Research Alliance discovered that molecules called type II interferons can trigger the immune system to over-produce the B cells that cause lupus inflammation. Type I interferons have already been shown to be very important in lupus which has led to exciting new drugs like anifrolumab […]
Nephritis
Lupus nephritis is kidney inflammation caused by systemic lupus erythematosus (SLE or lupus). SLE is an autoimmune disease—a disorder in which the body’s immune system attacks the body’s own cells and organs. Up to 60 percent of people with SLE are diagnosed with lupus nephritis, which can lead to significant illness and even death. Source: […]
LRA-Funded Study Finds Lazy Enzyme that Triggers Autoimmunity
April 14, 2021 Dr. Boris Reizis and his team, working with a group of clinical rheumatologists led by Dr. Jill Buyon, have made a connection between an enzyme that prevents people’s immune systems from reacting to their own DNA and lupus activity. In a paper just published in the Journal of Experimental Medicine they report […]
Promising News from Major Medical Meeting, EULAR
Updated June 5, 2020 One of the largest meetings for rheumatologists went virtual this year to enable scientists from around the world to share their latest findings amid the COVID-19 pandemic. EULAR, the e-Congress of the European League Against Rheumatism, runs June 3 -6, and LRA is pleased to share promising results from clinical trials […]
Grant Updates
The Lupus Research Alliance supports the full range of research from fundamental through translational and clinical studies. Most recently, the organization awarded six Novel Research Grants and seven Target Identification in Lupus (TIL) grants. PROMISING NOVEL GRANT AWARDS: The Lupus Research Alliance supports game-changing lupus research, and our Novel Research Grant program is exploring lupus […]
Q&A with Selena Gomez
Q: Why are you supporting the LRA’s Lift Up Lupus campaign? A: This was a tough year for all of us, and I am inspired by the sense of optimism conveyed by the LRA’s Lift Up Lupus campaign – and incredibly inspirational stories. There are many misconceptions surrounding lupus, and I hope the Lift Up […]
LRA Addressing Health Disparities Among Vulnerable Groups
February 20, 2020 The Lupus Research Alliance (LRA) works hard, often in concert with organizations like the National Minority Quality Forum to alleviate disparities in healthcare among groups at particular risk for lupus, including African-Americans as the group hardest hit by the disease. Several programs educate healthcare providers, patients and the public to better recognize […]