Research and Discovery Archives

Category: Research and Discovery

EULAR Presentation Showed Upadacitinib Improved Lupus Disease Activity

May 31, 2023 We are pleased to share encouraging news from EULAR, the annual meeting of the European Alliance of Associations for Rheumatology of Phase 2 data presented showing that upadacitinib improved SLE disease activity and time to first flare while lowering the need for steroids. Side effects were consistent with the known safety profile. Discovered and […] Read More

New England Journal of Medicine Publishes Positive Data of Litifilimab in Cutaneous Lupus Erythematosus

August, 2022 We are pleased to share positive results from the two-part Phase 2 LILAC study published in the New England Journal of Medicine showing that the investigational therapy litifilimab (BIIB059) lessened skin disease activity in cutaneous lupus erythematosus. There is a great unmet need for people with cutaneous lupus, a type of lupus with few treatment […] Read More

Lupkynis® (voclosporin) Granted Marketing Authorization in the European Union for Lupus Nephritis

September 21, 2022 Lupkynis® (voclosporin) was just granted marketing authorization in the European Union as a new treatment for adults with lupus nephritis, the kidney damage associated with lupus. The drug had also been approved this past January in the U.S. to treat adults with lupus nephritis in combination with a background immunosuppressive medication in […] Read More

Helping Overcome Lupus Effects on Mental Health

Updated March 11, 2022 Neuropsychiatric lupus affects 80-90% of people with lupus. In a video series hosted by the Young Leaders Board of the Lupus Research Alliance, Dr. Meggan Mackay explains How to know if you have neuropsychiatric lupus and offers ways to improve cognitive health. Dr. Mackay also describes a clinical trial she is […] Read More

Lupus Research Alliance Launches Two Major Initiatives to Increase Participation of Underrepresented Minorities in Lupus Clinical Trials and Research

January 27, 2022 NEW YORK, NY. January 27 — The Lupus Research Alliance (LRA) and its clinical affiliate Lupus Therapeutics (LT) announced two major initiatives to address underrepresentation of minorities in clinical trials and in the scientific research profession: Project CHANGE by LT and the Diversity in Lupus Research Program. The organization has tackled these […] Read More

Lupus Research Alliance Awards 2022 Lupus Insight Prize to Immunologist Dr. Akiko Iwasaki: Renowned immunology expert honored

June 23, 2022 The Lupus Research Alliance (LRA) is pleased to award its 2022 Lupus Insight Prize (LIP) to Akiko Iwasaki, PhD, for her discovery of the link between endogenous retroviruses and systemic lupus erythematosus (SLE). The award was presented to Dr. Iwasaki at the 22nd Annual Meeting of the Federation of Clinical Immunology Societies […] Read More

LRA-Funded Research Found a Connection Between the Epstein-Barr Virus Infection and MS as an Autoimmune Disease

February 4, 2022 A potential new cause of the autoimmune disease multiple sclerosis (MS) was discovered by researchers partly funded by the Lupus Research Alliance. Published in the prestigious journal Nature, the study results provide strong evidence that a virus can trigger the development of MS. The LRA invested in this work to help understand […] Read More

Encouraging Results with Obinutuzumab for Lupus Nephritis

February 13, 2022 The LRA is pleased to share a recently published paper reporting that the drug, obinutuzumab, showed positive results as a potential treatment for lupus nephritis in the phase 2 clinical trial NOBILITY. A medicine designed to attach a type of blood cell called B-cells with the marker CD20 on its surface, obinutuzumab […] Read More

LRA-Funded Research Aims at Preventing Heart Disease in Kids With Lupus

February 14, 2022 Being a kid isn’t always easy, but growing up with lupus makes it a much harder challenge. That’s why Harvard University’s Associate Professor Dr. Joyce Chang has a special place in her heart for these kids and chose to focus her career on their care. In honor of American Heart Month, we […] Read More

Catch Up on LRA News with Lupus Research Update Vol. 1, 2022

February 17, 2022 It’s with great pride that I share a sampling of the many extraordinary accomplishments of last year in our first Lupus Research Update of 2022. The Lupus Research Alliance (LRA) made important gains on many fronts—thanks to tremendous friends like you. I hope you share my pride because your support continues to be the catalyst behind every LRA accomplishment. […] Read More