New Study Led by LRA Scientific Advisor Explores the Role of Little-Studied Molecular Reactions in Preventing Organ Damage in Lupus
November 13, 2018 While much basic autoimmune research has focused on ways to foil the bad behavior of immune cells, Dr. Salmon and her team of investigators at the Hospital for Special Surgery/Weill Cornell Medicine have taken a very different tack. They have been studying whether enhancing the ability of the lining of the blood […]
A Tough Childhood Linked to Poor Adult Health and Immune System Disorders Like Lupus
May 9, 2019 New study results published in Arthritis Care & Research found that “adverse childhood experiences” are more common among people with lupus. In the University of California San Francisco study, adverse childhood experiences were categorized as abuse, neglect, and/or household challenges. Among people with lupus, 63.2 percent had at least one adverse childhood […]
Low-Dose Interleukin-2 Might be Effective for Lupus
September 24, 2019 Interleukin-2 at a low-dose may be effective in treating lupus, according to newly published results of a double-blind and placebo-controlled clinical trial. In this trial, 60 patients received either Interleukin-2 at a low dose of 1 million IU or placebo along with standard treatment for 12 weeks. The primary endpoint – the […]
Lupus Treatment Options
Today, doctors have more options to help patients manage lupus effectively, because treatments have expanded significantly in recent decades. Current medications for lupus include:
Lupus Industry Council
The Lupus Research Alliance Lupus Industry Council (LIC) includes pharmaceutical and biotechnology companies working together in the pre-competitive space to address common impediments to drug development in lupus and accelerate the pace of bringing new lupus therapies to the market. The LIC convenes quarterly to identify and discuss barriers in drug development, as well as […]
LRA-Funded Researchers Share Important Discoveries at Largest Rheumatology Meeting
November 19, 2020 The Lupus Research Alliance supported an impressive number — 30+ — of studies presented at ACR Convergence 2020, this year’s meeting of the American College of Rheumatology. Each year, researchers are selected to share their discoveries in talks and poster sessions, allowing medical professionals to keep up to date with the latest […]
Research Partners
Collaboration is one of the cornerstones of the Lupus Research Alliance’s research philosophy. We strive to identify and engage partners across disciplines and sectors to accelerate foundational and translational research in lupus. We welcome new partnering opportunities. Please contact Teodora Staeva, Ph.D. (tstaeva@lupusresearch.org)
Summary Highlights of Important Research Presented at ACR Convergence 2023
At the recent ACR Convergence 2023, the annual meeting of the American College of Rheumatology, important lupus clinical trial data and breakthrough foundational research were presented. Following are highlights of work funded by the Lupus Research Alliance or supported in partnership with industry through our clinical affiliate Lupus Therapeutics. CAR-T Cell Therapy is Showing Great […]
Lupus Industry Council Accomplishments
Return to Research Partners Drivers of Response and Non-response for SRI-4 and BICLA in Systemic Lupus Erythematosus (SLE) Clinical Trials Working Group Chair: Matthew Linnik (Eli Lilly) The paucity of success in late-stage clinical trials in systemic lupus erythematosus (SLE) remains a persistent and challenging problem with one of the key issues being the primary […]
Proliferative Lupus Nephritis
Inflammation of the kidneys caused by an autoimmune disease called systemic lupus erythematosus. The condition can cause hematuria and proteinuria, and it may progress to end-stage renal disease. The most severe form of lupus nephritis, called diffuse proliferative nephritis, can cause scars to form in the kidneys. Scars are permanent, and kidney function often declines […]
LRA-Funded Researchers Presented Cutting Edge Methods and Discoveries at the Annual Rheumatology Meeting
November, 2022 The Lupus Research Alliance (LRA) aims to support the best science to prevent, treat and cure lupus. This year during the annual American College of Rheumatology conference, ACR Convergence 2022, which took place from November 10 – 14 in Philadelphia, PA, more than 30 LRA-funded studies were presented by researchers to thousands of […]