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Tag: TIL

New Approach to Treating Lupus Nephritis

February 6, 2019 Scientists partly funded by the Lupus Research Alliance have found a potential new way to protect the kidneys in patients with lupus. A study led by Dr. Vicki Rubin Kelley of Brigham and Women’s Hospital in Boston, Massachusetts, suggests that blocking a molecule made by some cells in the kidney could reduce […] Read More

2017-18 Research Portfolio Summary

June 5, 2018 The Lupus Research Alliance is driven by one central goal — to improve the lives of people living with the disease, today and in the long term. We believe that scientific research is the most powerful way we can achieve this goal. Further, we believe that by both pushing the limits of scientific exploration and […] Read More

Skin Molecules Promote Cutaneous Lupus

June 24, 2019 Patients with cutaneous lupus develop rashes because immune cells move into the skin and cause inflammation. With a Target Identification in Lupus (TIL) grant from the Lupus Research Alliance, Dr. Jillian Richmond of the University of Massachusetts Medical School and colleagues found what lures the immune cells into the skin of people […] Read More

Lupus Research Alliance Announces New Grants For Translational Research

Jan. 10, 2018 Lupus Research Alliance Announces New Grants for Translational Research Seven Outstanding Investigators Chosen for Prestigious Lupus Research Grants The Lupus Research Alliance is proud to announce the recipients of its Target Identification in Lupus (TIL) grants designed to move research discoveries quickly from the laboratory to the patient’s bedside. Seven outstanding scientists […] Read More

New Study Partly Funded by LRA Reveals Novel Lupus Drug Targets

NEW YORK, NY – May 29. Researchers partly funded by the Lupus Research Alliance (LRA) have found possible new targets for drugs to treat lupus after snapping the first close-up of a molecule that promotes inflammation. The molecule that Target Identification in Lupus (TIL) grant recipient Dr. Roger Greenberg at University of Pennsylvania and Dr. […] Read More

Celebrate Clinical Trials Day May 20!

May 20, 2019 It’s Clinical Trials Day when the Lupus Research Alliance recognizes all the people we support who advance clinical research – scientists who identify and develop potential ways to diagnose, monitor and treat lupus,  researchers who design and conduct the studies to test these methods, and the volunteers who take part in the […] Read More

Potential Treatment for Sun Damage Discovered with LRA Funding

August 16, 2018 Exposure to the sun is hard on everyone’s skin, causing cells to die. But skin cells are much more vulnerable in people with lupus.  That reaction is called photosensitivity. A team of scientists led by Theresa Lu, MD, PhD, at Hospital for Special Surgery (HSS) in New York may have discovered why. […] Read More

Potential New Lupus Treatment Outperforms Hydroxychloroquine in Animal Study

November 28, 2018 Anti-malaria drugs such as hydroxychloroquine are common treatments for arthritis and heat rash in patients with lupus. A new study by Target Identification in Lupus grantee Keith Elkon, MD, of the University of Washington, Seattle, and colleagues suggests that a new drug they designed works better than the commonly prescribed hydroxychloroquine in […] Read More

Microchip Technology Charts New Ground

Sept. 7, 2017.  The study of T cells and B cells, their function, and the interaction between them that causes runaway inflammation and the progression of disease have been the subjects of numerous groundbreaking lupus investigations over the past decade. Today, Rong Fan, PhD, from Yale University, is building on these discoveries by using his […] Read More

New TIL Grantees Offer Novel Approaches

Sept. 7, 2017.  Grantees of our Target Identification in Lupus (TIL) program are remarkable scientific investigators whose ingenuity and determination are bringing new insights to lupus research. The Lupus Research Alliance congratulates each of these brilliant researchers in their quest to expand our understanding of lupus and ways to defeat it: Kerstin Nundel, PhD University […] Read More
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