image description

Tag: Janssen

Update from LRA’s President on COVID-19 Vaccines in Lupus

January 14, 2020 Dear Friends, Happy New Year! On behalf of all of us at the Lupus Research Alliance (LRA), thank you so much for your kindness and generosity in 2020 and prior years. 2021 starts off with some exciting milestones for the lupus community including a new treatment for lupus nephritis. But  Recently, our […] Read More

Third Vaccine Shield Against COVID-19 Rolling Out March 1, 2021

March 1, 2021 Americans gained a third weapon against COVID-19 this weekend with the availability of a third vaccine. On February 27, 2021, the U.S. Food and Drug Administration granted Emergency Use Authorization to the new vaccine from Janssen Pharmaceutical Companies of Johnson & Johnson to prevent COVID-19 in adults age 18 and older. The […] Read More

Study Shows Need for Greater Awareness of Biologics for Lupus

August 19, 2019 A new study led by Dr. S. Sam Lim of Emory University found a need for more awareness of biologic therapies among both black and white people with lupus.  Biologics are medicines that come from living cells to prevent, treat and cure human diseases, and are designed to have specific effects on […] Read More

Stelara® Effective Over One Year and Reduces Severe Flares

Results of two analyses from a Phase 2 study of Stelara® (ustekinumab) in lupus showed the drug’s effectiveness over one year. Both highlight the benefit of ustekinumab on disease activity and the rate of severe flares. Ustekinumab reduced the rate of severe flares four times as much as placebo by week 24. The rate of […] Read More

Lupus Research Alliance and Lupus Therapeutics Partner on New Phase 3 Trial Testing Potential Benefit of Ustekinumab (Stelara®) in Lupus

February 1, 2019 The Lupus Research Alliance announced that its affiliate Lupus Therapeutics is working with the pharmaceutical company, Janssen, to help conduct a Phase 3 trial to evaluate whether their drug ustekinumab (Stelara®) may offer benefit to people with lupus.  Called LOTUS, the international study is being conducted in over 200 sites, 20 of […] Read More

Lupus Research Alliance Prompted Stelara® Study for Lupus

Lupus Research Alliance welcomes compelling new data, presented at the American College of Rheumatology (ACR) annual meeting that demonstrated significant benefit for lupus patients treated with Stelara® (ustekinumab), a prescription medicine from the Janssen Pharmaceutical Companies. Stelara® is not approved for the treatment of lupus, but is approved by the FDA for certain autoimmune diseases. Through its drug repurposing program, the Lupus Research Alliance first identified Stelara® as a potential treatment for lupus and encouraged Janssen to pursue testing for this use. Read More

STELARA® Shows Positive Results

STELARA® (Ustekinumab) Shows Positive Results in Treatment of Systemic Lupus Erythematosus in Phase 2 Trial   60 percent of patients receiving STELARA® showed significant reductions in lupus disease activity vs. 31 percent of patients receiving placebo STELARA® showed significant improvements in various disease measures compared with placebo, including musculoskeletal, mucocutaneous, immunological markers and flares Janssen […] Read More