Updates and Events
2nd Annual Cars of Longmeadow

We’re so excited to be privileged enough to bring all of these incredible vehicles together for a charity car show. We would like to thank all of the car owners who have or will register for the event, and we would like to thank everyone, owners and spectators alike, for supporting a great cause – […] READ MORE

Lupus Luminary Luncheon for Science

Celebrating our 10th year of recognizing “women of achievement” across all industries, we have renamed our Lupus Handbag Luncheon to truly reflect the mission of the Lupus Research Alliance as the world’s leading lupus research organization. The Lupus Luminary Luncheon for Science will honor innovative and inspiring women while providing an opportunity to catch up […] READ MORE

Stelara® and Olumiant® Considered Promising by Lupus Expert

February 19, 2019 In Healio Rheumatology, Dr. Gregg Silverman, professor of medicine and pathology at NYU School of Medicine, provided an overview of potential lupus therapies in development.  He highlighted ustekinumab (brand name Stelara®) and baricitinib (brand name Olumiant®) as two drugs that look particularly promising. “The phase 2 extra-renal trial of baricitinib looks good; […] READ MORE

New Approach to Treating Lupus Nephritis

February 6, 2019 Scientists partly funded by the Lupus Research Alliance have found a potential new way to protect the kidneys in patients with lupus. A study led by Dr. Vicki Rubin Kelley of Brigham and Women’s Hospital in Boston, Massachusetts, suggests that blocking a molecule made by some cells in the kidney could reduce […] READ MORE

Protein Osteopontin Indicator of Lupus Nephritis, Shows Clinical Trial

February 1, 2019 Raised levels of a protein osteopontin were shown to indicate lupus nephritis and higher disease activity, in a new study conducted at 33 centers by top lupus researchers worldwide. Published in The Journal of Rheumatology, the study looked at results from 344 lupus patients. At the beginning of the study (baseline), patients […] READ MORE

Overcoming Challenges to Lupus Management

January 24, 2019 A recent review article in Lupus Science & Medicine provides a valuable overview of the “10 most important contemporary challenges in the management of SLE” according to a multidisciplinary team of clinicians, pharmacists and researchers from several clinics and patient organizations in France.  Their top 10 challenges include several critical factors that the […] READ MORE

Lupus Research Alliance and Lupus Therapeutics Partner on New Phase 3 Trial Testing Potential Benefit of Ustekinumab (Stelara®) in Lupus

February 1, 2019 The Lupus Research Alliance announced that its affiliate Lupus Therapeutics is working with the pharmaceutical company, Janssen, to help conduct a Phase 3 trial to evaluate whether their drug ustekinumab (Stelara®) may offer benefit to people with lupus.  Called LOTUS, the international study is being conducted in over 200 sites, 20 of […] READ MORE

Study Shows Kidney Transplant Improves Lupus Nephritis Survival

January 21, 2019 A study just published in Annals of Internal Medicine showed that kidney transplantation reduced deaths due to lupus nephritis — kidney inflammation caused by lupus. Up to 60 percent of people with SLE are diagnosed with lupus nephritis, which can lead to significant illness and even death. According to the National Institute of Diabetes […] READ MORE

Study shows: Stress, Depression and Pain are Major Contributors to Lupus Fatigue

January 18, 2019 An observational study published in Lupus of people with lupus found that of six factors,  stress, depression and pain contributed most to fatigue, one of the most debilitating symptoms of the disease. The study involved 116 ethnically diverse, primarily female participants (91%) diagnosed with lupus receiving care at university medical centers. Each […] READ MORE

Existing Asthma Medication Shows Effectiveness for Lupus

January 14, 2019 A small randomized Phase 1 study published in Arthritis & Rheumatology found that the existing asthma treatment omalizumab (Xolair) may improve lupus activity by reducing production of type 1 interferons.  The study involved 15 patients with lupus who had elevated amounts of an antibody immunoglobulin E and a minimum level of disease […] READ MORE

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