Lupus Research Update
Bold Initiatives … Tremendous Strides Breaking Through on Lupus Research

In 2018 the Lupus Research Alliance has taken daring chances, pursued bold initiatives, and made tremendous strides! We truly are breaking through on many pioneering fronts of lupus research — thanks to the unwavering generosity of donors at all levels of support. Throughout the year, the brilliant scientists we brought to the table ushered in […] READ MORE

Breaking Through – Uncovering a Probable Cause of Lupus:

An innate — and lifelong — curiosity about the most complex, unresolved questions in medicine has served John D. Mountz, MD, PhD, from the University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, well. For the past three decades he has made significant strides in piecing together some of the most disparate aspects […] READ MORE

Lupus Research Alliance-Funded Researchers Present Discoveries at ACR

October 29, 2018 More than 70 researchers who have received funding from the Lupus Research Alliance contributed to the scientific dialogue on lupus at the ACR|ARHP meeting this year. Following are highlights of specific discoveries the organization has supported: Tiring Out Rogue Cells Learning from cancer research, a team of scientists led by the inaugural […] READ MORE

Lupus Kidneys Copy Tumors’ Tactic to Protect Themselves

October 4, 2018 Abnormal immune cells invade the kidneys in patients with lupus and can damage the organs so severely that they stop working. But the kidneys defend themselves from these attacks by disabling these rogue cells, according to a new study from two scientists funded by the Lupus Research Alliance. Cancerous tumors similarly protect […] READ MORE

Cancer Study Shows How Body’s Trash Pickup Fails in Lupus

October 4, 2018 Immune cells called macrophages that normally clear away the body’s trash don’t do their jobs in lupus. Now, a study of cancer partly funded by the Lupus Research Alliance may explain how these macrophages promote lupus. Douglas Green, PhD, of St. Jude Children’s Research Hospital in Memphis, Tennessee, and colleagues found that […] READ MORE

Our Grantees Lead Investigation of Microbiome in Lupus

Sept. 5, 2018 Our microbiome includes all of the trillions of microorganisms that live in and on us. A recent review article about key discoveries on the role of the microbiome in lupus includes two researchers funded by the Lupus Research Alliance who may have discovered how some of these microbial passengers promote lupus by […] READ MORE

2017-18 Research Portfolio Summary

June 5, 2018 The Lupus Research Alliance is driven by one central goal — to improve the lives of people living with the disease, today and in the long term. We believe that scientific research is the most powerful way we can achieve this goal. Further, we believe that by both pushing the limits of scientific exploration and […] READ MORE

Why Is Heart Disease So Common in Lupus? New Study May Explain

April 24, 2018 Scientists funded by the Lupus Research Alliance may have discovered why patients with lupus are at risk for heart disease. Most recently, at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Dr. Mariana Kaplan and colleagues found that abnormal immune system cells are damaging patients’ arteries. Published in the journal […] READ MORE

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