lupus research alliance Archives

Tag: lupus research alliance

Bacteria in the Gut May be a Cause of Lupus and Flares: Shows Study Supported by Lupus Research Alliance

NEW YORK, NY. February 19. Pieces of bacteria that escape from the intestines may trigger lupus and associated disease flares in some patients, according to a new study partly funded by the Lupus Research Alliance. These findings may allow disease treatment with probiotics or diets that alter the mix of bacterial species in the intestines. […] Read More

Stelara® and Olumiant® Considered Promising by Lupus Expert

February 19, 2019 In Healio Rheumatology, Dr. Gregg Silverman, professor of medicine and pathology at NYU School of Medicine, provided an overview of potential lupus therapies in development. He highlighted ustekinumab (brand name Stelara®) and baricitinib (brand name Olumiant®) as two drugs that look particularly promising. “The phase 2 extra-renal trial of baricitinib looks good; […] Read More

New Approach to Treating Lupus Nephritis

February 6, 2019 Scientists partly funded by the Lupus Research Alliance have found a potential new way to protect the kidneys in patients with lupus. A study led by Dr. Vicki Rubin Kelley of Brigham and Women’s Hospital in Boston, Massachusetts, suggests that blocking a molecule made by some cells in the kidney could reduce […] Read More

Protein Osteopontin Indicator of Lupus Nephritis, Shows Clinical Trial

February 1, 2019 Raised levels of a protein osteopontin were shown to indicate lupus nephritis and higher disease activity, in a new study conducted at 33 centers by top lupus researchers worldwide. Published in The Journal of Rheumatology, the study looked at results from 344 lupus patients. At the beginning of the study (baseline), patients […] Read More

Overcoming Challenges to Lupus Management

January 24, 2019 A recent review article in Lupus Science & Medicine provides a valuable overview of the “10 most important contemporary challenges in the management of SLE” according to a multidisciplinary team of clinicians, pharmacists and researchers from several clinics and patient organizations in France. Their top 10 challenges include several critical factors that the […] Read More

Scientists Focus on Innate Immune System as Possible Lupus Treatment Approach

January 7, 2019 The 2018 Forum for Discovery opened with a series of lectures on new research on the role of our innate immune system in lupus and how discoveries may lead to new therapies. Roles of the cGAS Pathway in Lupus Zhijian (James) Chen, PhD, Professor of Molecular Biology at the University of Texas Southwestern […] Read More

Novel Therapeutic Approaches & Translational Challenges

One session at our recent scientific conference Forum for Discovery was devoted to meeting the need for new approaches to lupus and the challenges faced in “translating” what is learned by researchers into therapies that will help patients with lupus. Gerald Nepom, MD, PhD, Co-Chair of LRFs Scientific Advisory Board and Director of the Benaroya Research […] Read More

LRA Grantee Publishes Study on Diet in Lupus

December 22, 2018 Dr. Martin Kriegel and his colleagues at Yale University just published in Cell Host & Microbe an animal study partly funded by the Lupus Research Alliance that showed how diet may affect lupus. In this study, the team identified a specific bacteria, Lactobacillus reuteri, that was responsible for triggering an autoimmune response. […] Read More

Lupus Research Alliance Mourns the Loss of NIAMS Director, Dr. Stephen I. Katz

NEW YORK, NY. December 20. The Board of Directors and staff of the Lupus Research Alliance mourn the death of Stephen Katz, MD, PhD, a true champion for the lupus community. For over two decades, Dr. Katz has served as Director of the home institute for lupus at the National Institutes of Health (NIH), the […] Read More

Lupus Research Alliance Applauds FDA’s Fast Track Designation to Develop Baricitinib for Lupus

NEW YORK, NY. December 14. The Lupus Research Alliance is pleased to share good news about a potential new treatment for systemic lupus erythematosus (SLE). Yesterday, Eli Lilly and Company and Incyte Corporation announced that the U.S. Food and Drug Administration (FDA) granted Fast Track designation to baricitinib, which is being studied for the treatment of SLE. […] Read More

2018 Distinguished Innovator Awardees Named by Lupus Research Alliance

NEW YORK, NY. December 20. The Lupus Research Alliance is proud to announce the 2018 recipients of the Dr. William E. Paul Distinguished Innovator Award in Lupus and Autoimmunity: Nir Hacohen, PhD (right) and Vijay Kuchroo, DVM, PhD (left). Dr. Hacohen is seeking better ways to treat lupus kidney disease, the major cause of illness and […] Read More

5th Rally Against Lupus Raises $1+ Million for Lupus Research

November 30, 2018 This event is the brain child of Lupus Research Alliance Board member Nadeem Meghji, whose young niece suffers with lupus. Together with event Co-Chair Donald Provost and committee members Shannon Ching, Rachel Doyon, Andrea Drasites, and David O’Neill — Nadeem created a fun ping pong fundraising event at SPiN New York that has grown in size and stature every year. […] Read More