image description

Tag: lupus nephritis

FDA Expedites Existing Drug Gazyva for Lupus Nephritis

September 18, 2019 The LRA is pleased to share that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation to obinutuzumab (Gazyva®) for adults with lupus nephritis – the most common complication of lupus.  The FDA’s designation aims to  speed up  the development and review of drugs intended to treat a serious condition […] Read More

Lupus Therapeutics Expands Collaboration with Bristol-Myers Squibb to Test Potential Treatment for Lupus

New York, NY– June 27, 2019.  The Lupus Research Alliance (LRA) and its affiliate, Lupus Therapeutics, announced that it has broadened its collaboration with Bristol-Myers Squibb (BMS) to assess the investigational drug BMS-986165 as a potential new therapy for lupus nephritis (LN). This expands the existing collaboration in systemic lupus erythematosus (SLE). Lupus nephritis refers […] Read More

Better Lupus Care Reducing Deaths from Lupus Nephritis, Study Shows

April 22, 2019 Results of a study published in Arthritis & Rheumatology shows that end-stage renal disease and mortality due to lupus nephritis is down from 2010-2014. Researchers at Massachusetts General Hospital and Brigham and Women’s Hospital at Harvard Medical School extended an analysis done in 1995 through 2006.  Using the national registry of patients […] Read More

Patients with Lupus Nephritis-Related Kidney Disease Are Living Longer

March 28, 2019 A new study published this March in Arthritis & Rheumatology found that deaths among patients with end-stage renal disease (ESRD) due to lupus nephritis (LN) fell significantly — by 32% —over the past two decades. The study took into account deaths from all causes, including deaths from cardiovascular disease (CVD) and infection. […] Read More

Protein Osteopontin Indicator of Lupus Nephritis, Shows Clinical Trial

February 1, 2019 Raised levels of a protein osteopontin were shown to indicate lupus nephritis and higher disease activity, in a new study conducted at 33 centers by top lupus researchers worldwide. Published in The Journal of Rheumatology, the study looked at results from 344 lupus patients. At the beginning of the study (baseline), patients […] Read More

Study Shows Kidney Transplant Improves Lupus Nephritis Survival

January 21, 2019 A study just published in Annals of Internal Medicine showed that kidney transplantation reduced deaths due to lupus nephritis — kidney inflammation caused by lupus. Up to 60 percent of people with SLE are diagnosed with lupus nephritis, which can lead to significant illness and even death. According to the National Institute of Diabetes […] Read More

Good News from Aurinia Pharmaceuticals for Lupus Nephritis

September 25, 2018 Congratulations to Aurinia Pharmaceuticals for completing patient enrollment in the AURORA Phase 3 clinical trial ahead of schedule.  The company reported in a press release issued today that due to high patient demand, the target number of patients was surpassed with 358 lupus nephritis (LN) patients enrolled in sites across 27 countries. […] Read More

Looking at Iron as a Trigger for Lupus Nephritis

As the provider of life-giving oxygen to organ systems through its role in red blood cell production — the health benefits of iron are tremendous. This essential element is vital for proper growth throughout the body and for robust cellular health. But what happens when a good thing goes bad, and iron makes cells die? […] Read More
Stay informed about events, research developments, and ways you can help. Sign up for updates