April 22, 2019
Results of a study published in Arthritis & Rheumatology shows that end-stage renal disease and mortality due to lupus nephritis is down from 2010-2014.
Researchers at Massachusetts General Hospital and Brigham and Women’s Hospital at Harvard Medical School extended an analysis done in 1995 through 2006. Using the national registry of patients with end-stage renal disease, they identified all patients with end-stage renal disease due to lupus nephritis between 1995 – 2014. The mortality rate declined from 11.1 per 100 patient years in 1995-1999 to 6.7 in 2010-2014. Deaths from cardiovascular disease and infection declined by 63 percent from 2010-2014.
The team concluded that in the most recent years of the period between 1995-2014, there was a significant decrease in mortality among Caucasian, African American and Hispanic people with lupus, as well as reduced risk of death from cardiovascular disease and infection. “Collectively, these trends provide an important benchmark of improving care in this high-risk population.”