Research/Discovery
Our Grantees Lead Investigation of Microbiome in Lupus

Sept. 5, 2018 Our microbiome includes all of the trillions of microorganisms that live in and on us. A recent review article about key discoveries on the role of the microbiome in lupus includes two researchers funded by the Lupus Research Alliance who may have discovered how some of these microbial passengers promote lupus by […] READ MORE

Neovacs Announces the Results of its Phase IIb Study for Ifnalpha Kinoid in the Treatment of Lupus Which Allows to Proceed With the Clinical Development into Phase III

July 3, 2018 Neovacs announced the results of its Phase IIb clinical trial of the investigational agent IFNalpha Kinoid in patients with moderate to severe lupus (SLE). The results show that IFNalpha Kinoid very significantly reduced the levels of type I interferon genes in the blood and tissue cells of people with lupus. High levels […] READ MORE

2017-18 Research Portfolio Summary

June 5, 2018 The Lupus Research Alliance is driven by one central goal — to improve the lives of people living with the disease, today and in the long term. We believe that scientific research is the most powerful way we can achieve this goal. Further, we believe that by both pushing the limits of scientific exploration and […] READ MORE

Why Is Heart Disease So Common in Lupus? New Study May Explain

April 24, 2018 Scientists funded by the Lupus Research Alliance may have discovered why patients with lupus are at risk for heart disease. Most recently, at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, Dr. Mariana Kaplan and colleagues found that abnormal immune system cells are damaging patients’ arteries. Published in the journal […] READ MORE

Novel Tool Developed to Better Measure Lupus Trial Results

April 20, 2018 The Lupus Research Alliance Lupus Industry Council (LIC) met a key objective with the recent publication in the medical journal Arthritis & Rheumatology reporting on a new tool to better measure the effectiveness of potential drug treatments in clinical trials. The LIC aims to bring industry and academia together to work collaboratively, […] READ MORE

New Research Reveals How Mononucleosis Virus Could Promote Lupus

April 18, 2018 A new study by Lupus Research Alliance-funded researcher Dr. Matthew Weirauch of the Cincinnati Children’s Hospital Medical Center in Ohio and colleagues might explain how a common virus that causes mononucleosis also boosts the risk for lupus. The virus may be turning on human genes that promote the illness. The scientists, including […] READ MORE

Lupus Research Alliance Announces Nine Promising Novel Research Grant Awards

April 11, 2018 Nine Outstanding Investigators Receive Funding for Innovative Research on Lupus Causes, Pathways, and New Treatment Development Today, the Lupus Research Alliance announced nine new Novel Research Grants to support paradigm-changing lupus research. To conquer the complexity of lupus, the Novel Research Grants explore lupus from many perspectives, testing new theories about what […] READ MORE

Approved Immunosuppressant, Sirolimus, May Offer a Novel Lupus Treatment Option

April 5, 2018 A new clinical study published in the prestigious medical journal The Lancet found that sirolimus, a drug currently FDA approved to prevent organ transplant rejection, may offer a safe and effective treatment for lupus. In an accompanying editorial, Lupus Research Alliance Scientific Advisory Board Co-Chair Mary Crow, MD notes that in addition […] READ MORE

We Fund Top Scientists

April 5, 2018 Congratulations go to Dr. Zhijian ‘James’ Chen — just named the 2018 Lurie Prize in Biomedical Sciences recipient by the Foundation for the National Institutes of Health. The highly prestigious award recognizes Dr. Chen’s exceptional work that the Lupus Research Alliance proudly helped fund. His discovery of an enzyme cGAS uncovered an […] READ MORE

Bacteria Could be to Blame for Autoimmune Attacks

March 12, 2018 Bacteria Could be to Blame for Autoimmune Attacks Innovative novel research, co-funded by the Lupus Research Alliance, has produced a significant discovery about the role of bacteria and points to the potential for a vaccine or treatment that might prevent an autoimmune attack by suppressing specific bacteria. Led by Dr. Martin Kriegel […] READ MORE

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