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Glossary of Terms

Study Agent

A medicine, vitamin, mineral, food supplement, or a combination of them that is being tested in a clinical trial. Source: NCI Read More

Sponsor

The organization or person who initiates the study and who has authority and control over the study. Source: ClinicalTrials.gov Read More

Side effect

A problem that occurs when treatment affects healthy tissues or organs. Source: NCI Read More

Selection Bias

An error in choosing the individuals or groups to take part in a study. Ideally, the subjects in a study should be very similar to one another and to the larger population from which they are drawn. If there are important differences, the results of the study may not be valid. Source: NCI Read More

Retrospective study

A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition (controls). Researchers study the medical and lifestyle histories of the people in each group to learn what factors may be associated with the […] Read More

Retrospective cohort study

A research study in which the past medical records of groups of individuals who are alike in many ways but differ by a certain characteristic are compared for a particular outcome. Also called historic cohort study. Source: NCI Read More

Research Study

A scientific study of nature that sometimes includes processes involved in health and disease. For example, clinical trials are research studies that involve people. These studies may be related to new ways to screen, prevent, diagnose, and treat disease. They may also study certain outcomes or groups of people by looking at data collected in […] Read More