A study in which participates are divided by chance into separate groups that compare treatments or other interventions. Using chance to divide people into groups means the groups will be similar and the potential effects of the treatment can be compared more fairly. At the time of the trial it is not known which treatment […]
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When referring to an experiment or clinical trial, the process by which animal or human subjects are assigned by chance to separate groups that compare different treatments or other interventions. Randomization gives each participant an equal chance of being assigned to any of the groups.
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The person who is responsible for the scientific and technical direction of the entire clinical study. Source: ClinicalTrials.gov
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The main reason for the clinical trial. The types of primary purpose are: treatment, prevention, diagnostic, supportive care, screening, health services research, basic science, and other. Source: ClinicalTrials.gov
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The main result that is measured at the end of a study to see if a given treatment worked. What the primary endpoint will be is decided before the study begins. Source: NCI
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Research using animals to find out if a drug, procedure, or treatment is likely to be useful. Preclinical studies take place before any testing in humans is done. Source: NCI
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A study of a group of individuals taken from the general population who share a common characteristic, such as age, sex, or health condition. This group may be studied for different reasons, such as their response to a drug or their risk of getting a disease. Source: NCI
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Refers to a clinical study in which the patients in the control group receive a placebo. Source: NCI
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An inactive treatment or procedure that is intended to mimic as closely as possible a therapy in a clinical trial. Source: NCI
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