Neuropsychiatric systemic lupus erythematosus (NPSLE) describes a wide range of brain-involved symptoms — symptoms like not thinking clearly, forgetting things or even seizures, stroke and psychosis—experienced by up to 95% of lupus patients.
Source: Schwartz, Noa, Ariel D. Stock, and Chaim Putterman. “Neuropsychiatric lupus: new mechanistic insights and future treatment directions.” Nature Reviews Rheumatology (2019): 1.