Lupus Research Alliance

Mechanistic Clinical Awards

The Mechanistic Clinical Award ($750,000 for up to three years) supports pilot studies testing lifestyle interventions in concert with hypothesis-driven mechanistic analysis to illuminate the underlying effects.

2025 Funded Grants

sOX40 and sOX40L: Genetically motivated biomarkers with prognostic and predictive potential in SLE
Deborah Cunninghame Graham, PhD
King’s College London

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A Randomized, Double-Blind, Placebo-Controlled Trial of Quinacrine in Patients with Cutaneous Lupus
Victoria Werth, MD
Perelman School of Medicine at the University of Pennsylvania

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Rebekah Barnes December 10, 2025