Leading the way to a cure

Grant Funding Mechanisms

The Lupus Research Alliance has provided more funding to lupus and autoimmune disease research than any non-governmental agency in the world. To date, the organization has committed more than $172 million to advance lupus research. Current funding mechanisms include:

Target Identification in Lupus

Accelerating Progress Toward More Effective Treatments

Our TIL grant mechanisms give world-class researchers the opportunity to investigate promising studies through the funding mechanism of large grants for a period of two years. The aim of all lupus research funded under the TIL program is to quickly move a therapy from the laboratory to the patient's bedside.

The Lupus Research Alliance Scientific Advisory Board determines if an investigation is worthy of a TIL grant, which can be as much as $400,000. TIL grantees also have the opportunity to apply for continued funding up to $200,000.

Click here to learn more about our TIL awardees

Dr. William E. Paul Distinguished Innovator Awards in Lupus and Autoimmunity

$1-Million Grants for Innovative Projects Aiming to Uncover the Root Causes of Lupus That Can Drive to a Cure

The Dr. William E. Paul Distinguished Innovator Awards in Lupus and Autoimmunity were created to address the current lack of interventions that seek to reverse or prevent the disease. The only privately funded awards of this scale in lupus, the $1 million grant challenge global scientific leaders with a documented history of distinguished research to pursue highly innovative new ideas on the fundamental root causes of lupus that drive toward prevention or a cure. The Award seeks innovative discovery-driven proposals in human and/or animal model based lupus research.

Click here to learn more about our Distinguished Innovator awardees

Novel Research Grant

Novel Grants with Documented Success Support High-Risk, High-Reward Scientific Innovation

The Novel Research Grant program provides early-stage support with three-year $300,000 grants for high-risk, high-reward, idea-driven, novel research projects relevant to basic, translational or clinical investigation in lupus. Requiring creativity and innovation, projects advance novel scientific hypotheses in lupus, aim to stimulate investigation of underexplored approaches, and initiate transformative discoveries that can drive the development of safer and more effective treatments. Open to US-based investigators, the Novel Research Grants foster investigations into the fundamental mechanisms of lupus and its complications, explorations of novel approaches to understanding human lupus disease biology, and novel technologies. Applications from investigators in diverse disciplines, including those who may not have worked in lupus before, are encouraged. Continuation of previous research work is not appropriate for this grant mechanism.

Click here to learn more about our Novel Research Grant awardees

Functional Genomics and Molecular Pathways (FGMP) in SLE Grant*

Blazing New Avenues of Discovery

These studies, in uncovering a greater level of detail in how the immune system works, are expanding the list of therapeutic targets.

Selected investigators receive research grants of up to $350,000 for two years or Pilot Grants of up to $75,000 for one year. Grantees will focus on determining how the genes identified by SLEGEN may have a role in the disease, and provide further information about the molecular pathways modulated by these genes.

Click here to learn more about our FGMP awardees

*We are currently not funding any new grants under the Functional Genomics and Molecular Pathways in SLE mechanism.

Pilot Grant Program

Pursuing Research with Great Potential

Although this program has been postponed indefinitely, you may be interested in learning about past projects funded through the Lupus Research Alliance’s Pilot Grant Program. The program was designed to provide lupus research funding of up to $75,000 to investigators pursuing high-risk but promising approaches. The Pilot program’s streamlined application process is designed to entice new minds to lend their talents to lupus research. It also encouraged well-established names in the field to try their hands at highly novel investigations.

Click here to learn more about our PILOT awardees

Federal Funding for Lupus Research

Giving a Voice to Those with the Disease

We believe that the 1.5 million Americans who have lupus deserve the backing of our government. So in addition to direct support, the Lupus Research Alliance also advocates for increased federal funding for lupus research. And our efforts have paid off—with increased funds allocated through the Department of Defense’s Peer Reviewed Medical Research Program.

Click here to learn more about Advoacy and Public Policy

Research Partnerships

The Lupus Research Alliance has partnerships with several groups and organizations to work collaboratively in finding a cure across varied research models and methodologies.  Learn more here.

1.5 million

people in the U.S. have Lupus.

172 million

dollars committed to lupus research by the Lupus Research Alliance.

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