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Tag: Science Translational Medicine

LRA-Funded Study Sheds Light on Childhood Lupus Nephritis

A study partly funded by the Lupus Research Alliance (LRA) and published in Science Translational Medicine used advanced technology to study where and how immune cells interact within kidney tissue in lupus nephritis (LN), a severe kidney disease caused by systemic lupus erythematosus (SLE). By applying a cutting-edge tool called spatial transcriptomics, Shaun Jackson, MD, […] Read More

New Study Reveals How Autoantibodies Work Together to Drive Inflammation in Lupus

Researchers have made a significant breakthrough in understanding how the immune system is over-activated in systemic lupus erythematosus (SLE). In a new study partly funded by the Lupus Research Alliance (LRA), Jessica Hamerman, Ph.D. from the Benaroya Research Institute, and colleagues discovered that certain antibodies, previously understudied in lupus, can ramp up the activity of […] Read More

LRA-Funded Findings Suggest Way to Help Reverse Lupus Nephritis

June 15, 2020 A recently published study explored how an unconventional treatment method undergoing clinical trials in cancer patients could help lessen the severity of lupus nephritis (inflammation of the kidneys), a common and serious condition in people with lupus. Funded by the Lupus Research Alliance, this study, published in the journal, Science Translational Medicine, […] Read More