Pathogenesis of chronic cutaneous lupus erythematosus
In some people with systemic lupus erythematosus (SLE, lupus), immune cells from the blood enter the skin and inappropriately cause repeated injury, which is known as chronic cutaneous lupus erythematosus (CCLE). Dr. Craft will study how these cells cause damage using a combination of cutting-edge techniques to study both the damage-causing immune cells and the injured skin cells. The study will reveal new understanding of what causes chronic cutaneous lupus so new therapies for people living with this debilitating condition can be developed.
What this study means for people with lupus
This study will reveal more effective therapy approaches for people living with damage to the skin caused by lupus.