October 22, 2020 Aurinia Pharmaceuticals announced that data taken from a combined analysis of two trials, AURA-LV and AURORA underscored the potential for voclosporin to offer a tool to treat lupus nephritis. Results from 534 patients from both trials was presented at the American Society of Nephrology Kidney Week 2020 meeting by Dr. Brad Rovin, […] READ MORE
October 22, 2020 Great event; I learned a lot and will have a discussion with my doctor about participating in a trial. It was excellent, and the website is very easy to use. I learned that the medicines you take for lupus are not designed for the disease while the ones you take in a […] READ MORE
October 22, 2020 To take or not to take the COVID-19 vaccine when one is available — that is the question on everyone’s minds, and we need all of your answers to accurately represent people with lupus and their supporters! As coronavirus vaccines are being developed and tested, the Lupus Research Alliance recently convened a […] READ MORE
October 21, 2020 In a recent study published in Nature Immunology, LRA Lupus Insight Prize recipient Dr. Ignacio Sanz and colleagues found that the immune response in patients hospitalized with severe COVID-19 was different from that in patients with mild disease, and that the immune response in severely ill COVID-19 patients was more like a lupus flare. They saw that among severely ill COVID-19 patients, some immune cells called B cells reproduced unchecked, and […] READ MORE
October 15, 2020 Some people respond to COVID-19 by releasing high amounts of immune proteins called cytokines, which form when the body detects a foreign invader. But release of excessive amounts of cytokines leads to a large immune response that can cause organ damage. With grant support from the Lupus Research Alliance, Dr. Roberto Caricchio […] READ MORE
October 8, 2020 People with lupus often develop complications in major organs such as the kidneys, called Lupus Nephritis (LN). By taking pictures of the kidneys with a special microscope, Dr. Janos Peti-Peterdi and his team at Keck School of Medicine of University of Southern California (USC) found a chain of molecules that leads to […] READ MORE
October 1, 2020 In a recent Lupus Research Alliance supported study published in Frontiers in Immunology, Dr. Ziaur Rahman linked molecules called TLR7 and type II interferon to impairing the ability of immune cells to do their job. These findings support further development by several companies of lupus treatments that block TLR7 and type II […] READ MORE
New York, NY. September 25 — The Lupus Research Alliance presented its 2020 Lupus Insight Prize to Jane Salmon, MD for her work in improving the health of pregnant women with lupus and antiphospholipid syndrome. The prize was formally “presented” to Dr. Salmon by LRA Scientific Advisory Board Chair Gary Koretzky, MD during a virtual […] READ MORE
Lupus Clinical Trials Redefined: You Make the Difference Lupus Clinical Trials Virtual Fair October 17, 2020 10:00 am to 1:00 pm ET Register Here Lupus clinical trials are still underway despite COVID-19. Making the process safer and easier for patients has never been more important. What is a clinical trial exactly? Why should I get involved […] READ MORE
September 16, 2020 NEW YORK, NY. The Lupus Research Alliance welcomes positive BLISS-LN Phase 3 data published in this week’s New England Journal of Medicine, demonstrating that GSK’s drug Benlysta® (belimumab) significantly improved kidney function in adults with lupus nephritis, the most common severe complication of lupus causing inflammation and serious damage to the kidney. The […] READ MORE
September 3, 2020 PPD, Inc. issued a press release today announcing its collaboration with the Lupus Research Alliance affiliate Lupus Therapeutics to optimize lupus clinical research among its pharmaceutical and biotech clients. As a contract research organization, PPD helps its clients design and implement clinical trials. PPD expects to gain from Lupus Therapeutics’ deep clinical […] READ MORE
August 25, 2020 A study started four years ago and conducted by 23andMe provided many insights about lupus as a complex disease that is extremely difficult to diagnose and treat. While the survey of nearly 6,000 participants did not find new genetic factors causing lupus as hoped, the study confirmed that lupus can run in […] READ MORE