Research/Discovery
Lupus Redfined: You Make The Difference

October 22, 2020 Great event; I learned a lot and will have a discussion with my doctor about participating in a trial. It was excellent, and the website is very easy to use. I learned that the medicines you take for lupus are not designed for the disease while the ones  you take in a […] READ MORE

Positive Results on Anifrolumab for Lupus Published in New England Journal of Medicine

December 18, 2019 The Lupus Research Alliance (LRA) welcomes additional positive results published today in the New England Journal of Medicine online edition from AstraZeneca’s Phase 3 TULIP-2 trial studying the investigational biologic anifrolumab as a treatment for systemic lupus erythematosus (SLE or lupus).  The new study provides further details showing that anifrolumab, which targets […] READ MORE

LRA Pleased to Share News of Lupus Nephritis Clinical Trial Launch

October 1, 2019 The Lupus Research Alliance is pleased to share news about the launch of EQUALISE, a Phase 1b trial that will evaluate the safety and tolerability of an experimental compound itolizumab at various doses in a small group of patients with systemic lupus erythematosus (SLE) and lupus nephritis. Sponsored by the biotechnology company […] READ MORE

FDA Expedites Existing Drug Gazyva for Lupus Nephritis

September 18, 2019 The LRA is pleased to share that the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy Designation to obinutuzumab (Gazyva®) for adults with lupus nephritis – the most common complication of lupus.  The FDA’s designation aims to  speed up  the development and review of drugs intended to treat a serious condition […] READ MORE

VALUE Study Results Reported at EULAR

MADRID, Spain. June 13, 2019 – Results of the first clinical trial sponsored by the Lupus Research Alliance and conducted through its Lupus Clinical Investigators Network (LuCIN) were presented today at the European Congress of Rheumatology (EULAR) 2019.  Entitled VAlidation in LUpus of an Electronic Patient Reported Outcomes Tool (VALUE), the study showed that a […] READ MORE

A Promising New Therapy

April, 2019 As our name implies, the Lupus Research Alliance aims to forge partnerships and bring other players  to the table to better understand and treat lupus — and our latest venture holds the promise of a new therapy. We — and our affiliate, Lupus Therapeutics — are about to collaborate with Takeda Pharmaceutical Company […] READ MORE

Lupus Therapeutics Partners with Takeda to Test Potential Treatment for Lupus

New York, NY– March 1.  The Lupus Research Alliance and its affiliate, Lupus Therapeutics announced a collaboration with Takeda Pharmaceutical Company Limited, to evaluate the investigational biologic TAK-079 as a potential new therapy for lupus in a Phase 1 trial (NCT03724916).  The national study will be conducted in 20 research centers throughout the country, many […] READ MORE

Bold Initiatives … Tremendous Strides Breaking Through on Lupus Research

In 2018 the Lupus Research Alliance has taken daring chances, pursued bold initiatives, and made tremendous strides! We truly are breaking through on many pioneering fronts of lupus research — thanks to the unwavering generosity of donors at all levels of support. Throughout the year, the brilliant scientists we brought to the table ushered in […] READ MORE

Breaking Through – Uncovering a Probable Cause of Lupus:

December, 2018 An innate — and lifelong — curiosity about the most complex, unresolved questions in medicine has served John D. Mountz, MD, PhD, from the University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, well. For the past three decades he has made significant strides in piecing together some of the most […] READ MORE

Together, ManyOne Can make a difference!