In Situ Adaptive Immunity in Lupus Tubulointerstitial Inflammation
Marcus Clark, MDThe University of Chicago
Redesigning Dnase1L3 for the Treatment of Systemic Lupus Erythematosus
Lupus Mechanisms and Targets Award (LMTA)
The Lupus Mechanisms and Targets Award provide up to $200,000/year total costs for up to 3 years. They support highly meritorious research focused on the identification and scientific and/or clinical advancement of therapeutic targets that will lead to new therapies for lupus.
2020 Funded Grants
The University of Chicago
Candidate Pathobiont in Lupus: Genomic Variation and Pathogenesis
Gregg J Silverman, MDNew York University School of Medicine
IgA-containing immune complexes in SLE
Jessica A. Hamerman, PhDBenaroya Research Institute at Virginia Mason
Dynamic Regulation of Signaling Pathways in SLE
Alessandra B Pernis, MDThe Hospital for Special Surgery
Redesigning Dnase1L3 for the Treatment of Systemic Lupus Erythematosus
Roger Bryan Sutton, PhDTexas Tech University Health Sciences Center
2019 Funded Grants
Targeting the Inactive X for Correcting Dosage Imbalances in Lupus
Montserrat Anguera, PhDUniversity of Pennsylvania School of Veterinary Medicine, Philadelphia
Intrinsic B cell epigenetic mediators as therapeutic targets in lupus
Paolo Casali, MDUniversity of Texas Health Science Center at San Antonio
Cytokine Immunoregulatory Strategy to Target SLE Autoreactive B Cells
Hui-Chen Hsu, PhDUniversity of Alabama at Birmingham
Targeting Follicular Helper T cell Metabolism in Lupus
Hongbo Chi, PhDSt. Jude Children's Research Hospital, Memphis, Tennessee
Relieving ER Stress in Lupus Neutrophils
Jason Knight, MD, PhDUniversity of Michigan, Ann Arbor
Ptprz: A Therapeutic Target for Lupus Nephritis
Vicki Kelley, PhDHarvard Medical School
2018 Funded Grants
Targeting Follicular Helper T Cells in Lupus
Joseph Craft, MDYale School of Medicine
The cyclic GAMP Pathway in SLE
Keith Elkon, MDUniversity of Washington
Targeting Interferon-Stimulated Transcription as a Novel Lupus Therapy
David Levy, PhDNYU School of Medicine
PTPN22 function in human B cells and inhibition to reset tolerance in SLE
Eric Meffre, PhDYale School of Medicine
Targeting peripheral T cell-B cell interactions in SLE
Deepak Rao, MD, PhDHarvard Medical School
Targeting the CXCR3 Chemokine Axis in Cutaneous Lupus
Jillian Richmond, PhDUniversity of Massachusetts Medical School
Mammalian free glycan, glycocalyx and anti-glycan antibody in lupus
Nan Yan, PhDUniversity of Texas Southwestern Medical Center