HOME
Leading the way to a cure

LUPUS NEWS

Cyclophosphamide Tied to ‘Relatively Small’ Lymphoma Risk Among Patients with Lupus

May 10, 2013

Patients with systemic lupus erythematosus who took immunosuppressive medications did not necessarily increase their risk for lymphoma, and those exposed to cyclophosphamide had only a relatively low rate of incidence, according to study results.

In case-cohort analyses within a multisite systemic lupus erythematosus (SLE) cohort, researchers studied 75 patients with lymphoma (mean age at entry, 45.2 years; 80% women) and 4,961 cancer-free patients (mean age, 38.5 years; 90.9% women). Regression models generated adjusted hazard ratios for lymphoma, time-dependent exposures to immunomodulators (cyclophosphamide, azathioprine, methotrexate, mycophenolate, antimalarial drugs and glucocorticoids), demographics, calendar year, Sjögren’s syndrome, SLE duration and disease activity.

***

Click here to read the full article.

Source: Healio


Cyclophosphamide Tied to ‘Relatively Small’ Lymphoma Risk Among Patients with Lupus

May 10, 2013

Patients with systemic lupus erythematosus who took immunosuppressive medications did not necessarily increase their risk for lymphoma, and those exposed to cyclophosphamide had only a relatively low rate of incidence, according to study results.

In case-cohort analyses within a multisite systemic lupus erythematosus (SLE) cohort, researchers studied 75 patients with lymphoma (mean age at entry, 45.2 years; 80% women) and 4,961 cancer-free patients (mean age, 38.5 years; 90.9% women). Regression models generated adjusted hazard ratios for lymphoma, time-dependent exposures to immunomodulators (cyclophosphamide, azathioprine, methotrexate, mycophenolate, antimalarial drugs and glucocorticoids), demographics, calendar year, Sjögren’s syndrome, SLE duration and disease activity.

***

Click here to read the full article.

Source: Healio



1.5 million

people in the U.S. have Lupus.

90 million

dollars committed to lupus research by the Alliance for Lupus Research.


We're walking across the United States to raise awareness and funds for lupus research.

Can't make it? Join our National Virtual Walk to participate anytime, anywhere.


Show your support by visiting the Alliance for Lupus Research online store. Discover the perfect gift, or prepare for a walk with our selection of apparel and accessories.

Powered by Convio
nonprofit software