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Biocruces Researchers Develop New Protocol for Treatment of Lupus Nephritis

February 1, 2014

The international Autoimmunity Review scientific journal has just published an advanced online version of the research undertaken by the Autoimmune Diseases Group at the BioCruces Health Research Institute (in Barakaldo, near Bilbao) and which presents a new treatment regimen for lupus nephritis.

This new protocol is characterised by the use of a very much lower dosage of oral corticoids (prednisone), which to date have been administered in high doses. The results show that the new treatment protocol drawn up by the BioCruces researchers at least equals standard treatment, obtaining an earlier response, at the same time notably reducing the adverse effects linked to glucocorticoids.

As Doctor Guillermo Ruiz-Irastorza, in charge of the Autoimmune Diseases Group at the BioCruces Health Research Institute, explained “lupus nephritis (inflammation of the kidney due to systemic lupus erythematosus) affects 35% to 40% of patients with lupus, an autoimmune disease especially affecting young women; in fact, it is the most serious frequent organ condition. To date, treatment has been based on the combination of immunosuppressant drugs with prednisone in high doses - in general one milligram per kilo of weight per day, i.e. 50 or 60 milligrams daily”.

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Click here to read full article.

Source: HealthCanal.com


Biocruces Researchers Develop New Protocol for Treatment of Lupus Nephritis

February 1, 2014

The international Autoimmunity Review scientific journal has just published an advanced online version of the research undertaken by the Autoimmune Diseases Group at the BioCruces Health Research Institute (in Barakaldo, near Bilbao) and which presents a new treatment regimen for lupus nephritis.

This new protocol is characterised by the use of a very much lower dosage of oral corticoids (prednisone), which to date have been administered in high doses. The results show that the new treatment protocol drawn up by the BioCruces researchers at least equals standard treatment, obtaining an earlier response, at the same time notably reducing the adverse effects linked to glucocorticoids.

As Doctor Guillermo Ruiz-Irastorza, in charge of the Autoimmune Diseases Group at the BioCruces Health Research Institute, explained “lupus nephritis (inflammation of the kidney due to systemic lupus erythematosus) affects 35% to 40% of patients with lupus, an autoimmune disease especially affecting young women; in fact, it is the most serious frequent organ condition. To date, treatment has been based on the combination of immunosuppressant drugs with prednisone in high doses - in general one milligram per kilo of weight per day, i.e. 50 or 60 milligrams daily”.

***

Click here to read full article.

Source: HealthCanal.com



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