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Lupus Research Update: 2012 Volume 3

Volume 3, 2012 - Online Edition | In This Issue


Looking at T Cell Function to Better Understand Lupus >
Back to Basics — T Cells... B Cells... And Lupus >
Researching B Cells Reveals Clues About Lupus >
Faces of Lupus: Sisterly Love in Michigan Benefits Everyone with Lupus >
Genetic Gateways to Understanding Lupus - New ALR Grant Awardees >
Lupus News Corner >

Genetic Gateways to Understanding Lupus - New ALR Grant Awardees

Each of the following investigators was recently awarded grants through the ALR’s Functional Genomics and Molecular Pathways (FGMP) program. This grant mechanism funds forward-looking studies that focus intensely on understanding the genetic characteristics of lupus.

Richard Bucala, MD, PhD
Yale University, CT
Function of the Polymorphic MIF Locus in SLE

Jane Buckner, MD
Benaroya Research Institute at Virginia Mason, WA
The Impact of Genetic Variants on B cell Development and Function in SLE

Jose Crispin, MD
Beth Israel Deaconess Medical Center, MA
Mechanisms through which protein phosphatase 2A (PP2A) promotes SLE

Yun Deng, MD
University of California, Los Angeles, CA
Dose differential miRNA binding explain allelic risk of TLR7 for SLE

Di Feng, PhD
UMDNJ-New Jersey Medical School, NJ
Identifying IRF5-mediated pathways in normal and SLE B cells

Peter Gregersen, MD
The Feinstein Institute for Medical Research, NY
Functional Analysis of Csk: A Newly Defined Risk Gene for Lupus

Terry Means, PhD
Massachusetts General Hospital (The General Hospital Corp.), MA
In vivo validation and characterization of allelic variants in lupus

William Tansey, PhD
Vanderbilt University Medical Center, TN
Characterization of PHRF1; a ubiquitin ligase implicated in SLE

Betty Tsao, PhD
University of California, Los Angeles, CA
Functional Genomics of SLE associated SMG7/NMNAT2 Locus


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