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Lupus Research Update: 2010 Volume 2

Volume 2, 2010 - Online Edition | In This Issue


The Next Phase in Advancing Genetic Science >
Brilliant Minds Search for Answers >
Uncovering New Paths to Treatment for Lupus Nephritis >
Faces of Lupus: A Volunteer Who has it All >
Lupus Experts Convene at International Congress >
Lupus News Corner >

Brilliant Minds Search for Answers

The ALR has greatly advanced genetic lupus research through its pioneering funding of the SLEGEN Consortium. Since the Consortium’s discovery three years ago of possible genetic markers for developing lupus, the ALR has been putting more resources into this promising field by establishing its new program of Functional Genomics and Molecular Genetic Pathways Grants.

The ALR is pleased and proud to announce this year’s grantees. We wish them continued success in unlocking the mysteries of lupus:

Marta Alarcon-Riquelme, M.D., Ph.D.
Oklahoma Medical Research Foundation
Dissecting a Novel Molecular Genetic B-Cell Pathway in Lupus

Robert Clancy, Ph.D.
New York University School of Medicine
ITGAM R77H: Genotype/Phenotype Relationships in Dendritic Cells

I-Cheng Ho, M.D., Ph.D.
Brigham and Women’s Hospital, Inc.
Protective roles of Ets1 in SLE

Fred Perrino, Ph.D.
Wake Forest University Health Sciences
TREX1 mutations in SLE

Earl Silverman, M.D.
The Hospital for Sick Children (Canada)
How Genes determine SLE Phenotype and Outcome

Jun Yan, M.D., Ph.D.
University of Louisville
Regulation of Autoreactive B Cells by Integrin ITGAM/CD11b

Listing of 2010 awards is for informational purposes only. Funds will be awarded upon successful negotiations.

How does genetics differ from genomics?

Genetics refers to the study of genes and the roles they play in inheritance — the specific traits or conditions that are passed down from one generation to another. Genetics involves scientific studies of genes and their effects.

Genomics describes the study of all of a person’s genes —including the interactions of genes with each other and with the person’s environment. Genomics includes
the scientific study of complex diseases such as lupus because it may be caused by a combination of genetic and environmental factors.


1.5 million

people in the U.S. have Lupus.

100 million

dollars committed to lupus research by the Alliance for Lupus Research.


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