Leading the way to a cure

Lupus Research Update: 2010 Volume 1

Volume 1, 2010 - Online Edition | In This Issue

The Expanding Horizons of Lupus Research >
A Message from the President >
Turning Promising Ideas Into Effective Treatments >
New Drug Shows Positive Results In Clinical Trial >
ALR Announces 2010 TIL Grantees >
Lupus News Corner >

New Drug Shows Positive Results In Clinical Trial

How the drug worksAn exciting new development in lupus research comes from the Belgian drug company — UCB — which recently announced promising new results from Phase II of a clinical investigation of its new drug Epratuzumab.

The clinical development program of Epratuzumab has been specifically designed to target moderate-to-severe symptoms in people with lupus. Recently, data from the Phase II study has demonstrated a meaningful treatment effect over placebo in 227 patients who had moderate to severe disease activity in multiple organ systems. The data from this study will be presented at the World Lupus Congress meeting in Vancouver, BC in June of this year.

Lupus is a complex disease that exhibits many varied symptoms — and Epratuzumab holds particular promise for lupus patients who take steroids. Anna Barry, Clinical Program Director, from UCB explains: “Our new drug may reduce the signs and symptoms of the disease in patients with moderate to severe lupus activity across many body systems — and that hopefully will translate into less use of corticosteroids, which have many side effects when used over long periods. It is exciting to be on the brink of a new and novel treatment, which may provide hope for hundreds of thousands of people around the world.”

With the success of Phase II, UCB is moving ahead to Phase III, to evaluate the drug’s effectiveness on a larger patient population.

1.5 million

people in the U.S. have Lupus.

172 million

dollars committed to lupus research by the Lupus Research Alliance.

We're walking across the United States to raise awareness and funds for lupus research.


Show your support by visiting the Lupus Research Alliance online store. Discover the perfect gift, or prepare for a walk with our selection of apparel and accessories.

Powered by Blackbaud
nonprofit software