Leading the way to a cure

Lupus Research Update: 2009 Volume 4

Volume 4, 2009 - Online Edition | In This Issue

Thinking Outside of Boundaries >
Message from the President >
The ALR Holds Key Industry Workshop on Lupus Clinical Trials >
Faces of Lupus — Thanks to Walkers on our 10th Anniversary >
Jets Kick Off Season of Hope >
Take Advantage of Tax Benefits — Make Your Year-End Gift Today! >
A "Driving" Force for Lupus Research >
Good News from Lupus Clinical Trials >

Good News from Lupus Clinical Trials

On November 2, 2009, Human Genome Sciences and their partner GlaxoSmithKline released encouraging news from their Phase III trials of Benlysta, a possible new drug for lupus.

Benlysta specifically recognizes and inhibits the biological activity of B-lymphocyte stimulator, or BLyS, a naturally occurring protein that promotes the development of B-lymphocyte cells into mature plasma cells in lupus. In autoimmune diseases such as lupus, elevated levels of BLyS are believed to contribute to the production of auto-antibodies that attack and destroy the body's own healthy tissue.

Previous clinical studies have suggested that Benlysta can reduce auto-antibody levels. Now the results of Phase III trials suggest that Benlysta can also reduce disease activity.

The ALR commends Human Genome Sciences and their partner GlaxoSmithKline for this extraordinary work. We look forward to keeping all of our supporters abreast of future developments from this exciting inquiry.

"Our hope is that the success of this trial will lead to FDA approval of the first new drug for lupus in 50 years." Barbara Boyts, President ALR

1.5 million

people in the U.S. have Lupus.

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dollars committed to lupus research by the Lupus Research Alliance.

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