Leading the way to a cure

Lupus Research Update: 2008 Volume 3

Volume 3, 2008 - Online Edition | In This Issue

Message From The President >
ALR Awards Record Number of Research Grants >
Progress: Congress Proposes Increased NIH Funding >
Lupus Research Progress >
The Faces of Lupus: Laura and Neil Gever >
New York Jets Honor ALR Supporter and Volunteer Joseph Trunfio of Atlantic Health >
New Community Walks Raise Mega-Funds for Research >
Shoe News — ALR Walk Update >
ADVOCACY CORNER — Standing Up for Federal Lupus Research Dollars >
ADVOCACY CORNER — "Could I Have Lupus?" Awareness Campaign Launches >

ALR Awards Record Number of Research Grants

We are extremely proud to share with you another milestone in the search for innovative treatments and a cure for lupus. In 2008, the Alliance for Lupus Research (ALR) has awarded the largest number of grants in the history of our organization – distributing 27 grants to researchers around the world.

You can read the complete list of new grantees in the enclosed insert. We’re certain you’ll be proud to see the many groundbreaking studies currently underway. Among the funded projects this year is the work of Dr. Shiv Pillai of Massachusetts General Hospital in Boston. Dr. Pillai is examining the gene that encodes an enzyme called sialic acid acetyl esterase (SIAE).

Preliminary studies in both humans and mice have established the possible link between SIAE and autoimmune diseases like lupus and rheumatoid arthritis. The goal of continued research is to firmly establish this link and lay the groundwork for future treatments.

Another of the many promising projects is Dr. Cornelia Weyland’s work at Emory University in Atlanta, Georgia. Studies show that people with lupus are at higher risk for heart attacks and strokes. Dr. Weyland is studying a particular pathway of inflammation in atherosclerotic plaque that may contribute to acute heart attacks.

By identifying the inflammatory signals that trigger specialized immune cells to secrete high levels of interferon-alpha and lead T cells to destroy plaquestabilizing tissue, Dr. Weyland’s research could lead to major breakthroughs in cardiovascular health for people with lupus.

We look forward to reporting back to you on the progress of these and all of the other important research projects made possible by your support. Since our founding in 1999, ALR has committed more than $50 million to lupus research and become the world’s largest private source of lupus research funds. You can read more about research we are funding at www.lupusresearch.org/research

1.5 million

people in the U.S. have Lupus.

172 million

dollars committed to lupus research by the Lupus Research Alliance.

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